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Agmatine and Kratom: Is it a Good Idea to Combine?

Those first few months of the kratom experience are often the most exciting. With new strains and forms at every turn, it’s often a treat to find your stash running low since that means you can start browsing to find your next kratom purchase. But after a year, once you’ve tried all the choices on those kratom store shelves, you might find things getting a little boring. You might want to try agmatine and kratom to make things a little exciting.

Fortunately, agmatine is one of the potentiators that can mix up the experience. Agmatine is a popular health supplement that’s praised for its alleged ability to enhance physical performance, among many other benefits. So it was only really a matter of time before the kratom population started taking the stuff with their dose of speciosa. But how well does it work, and is it even safe?

What is Agmatine?

Also called guanadine, agmatine is a naturally occurring chemical substance that’s found in plants, animals, and humans. It’s presently an experimental and investigational drug that’s being studied for its benefits in human health and wellness. While the studies aren’t conclusive, most reports demonstrate that agmatine may have advantages in various areas.

Most agmatine products sold on the market come in the form of dietary supplements targeted at individuals interested in improving their physical and athletic performance, especially in the gym.


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Kratom and Agmatine — Can You Take Them Together?

Visit the kratom Subreddit, and you’ll find countless threads that discuss the benefits of agmatine when taken together with kratom. But it’s not all conjecture. According to a study published in 2003, agmatine may play a role in certain receptor function modulation that might indirectly increase kratom’s potential effects.

That said, many kratom enthusiasts stand by agmatine as a potentiator — both effectively enhancing the effects of kratom while allowing users to taper down their doses to reduce tolerance and dependence on the kratom herb.

While the literature on the topic of kratom and agmatine together may be limited, anecdotal sources claim that taking the two together may elevate the benefits of kratom, especially the white and green vein varieties. Some of the reported effects of kratom and agmatine together include:

image of kratom and agmatine can you take them together

  • Improved physical performance
  • Higher energy levels
  • Upbeat, enhanced mood
  • Increased stamina and endurance
  • Decreased need for sleep

Do note that using agmatine with red vein kratom isn’t usually recommended by kratom users because of the contradicting effects of the two substances. On another note, it’s important to watch your doses in case you decide to use agmatine with white or green vein kratom since they do heighten each other’s effects.

Is It Safe?

Before you let all of those Reddit threads make you jump the gun, it helps to know how safe the combination can actually be. As of writing, there are no scientific sources that can confirm or deny the safety of the kratom and agmatine combo. Another thing worth mentioning is that everyone reacts differently to supplements and substances.

As with any other health or wellness regimen, always consult with your doctor. And in case you decide to give it a try, start at the lowest possible dose for both substances. There will be some trial and error involved in trying to figure out the right dose for your situation. Still, it’s recommended to start small and work your way up to avoid any side effects or adverse reactions associated with larger amounts.

And finally, ditch the combination at the first signs of a negative body response. These include headaches, dizziness, stomach discomfort, nausea, and fatigue, especially if you’re still taking small doses. All are signs that your body might not be too happy with the mixture.

image of is it safe to take kratom and agamite together

How to Take Kratom with Agmatine

Agmatine is available as capsules, tablets, or as a powder. Ideally, you should take your agmatine dose at the same time you take your kratom since they’re digested and metabolized at roughly the same pace. Alternatively, you can mix together agmatine powder with kratom powder and add it to a shake or smoothie for a more palatable dose.

Over to You

Are agmatine and kratom a proven combination? Well, not really. So it pays to tread with caution. But considering all of the positive reports from verified kratom users across the web, there might be some promise for the interesting union. Nonetheless, if you’re looking to give it a shot, it pays to know what you’re getting yourself into. Manage your dose, consider your body’s response, and adjust accordingly to get the perfect ratio and amount for your specific needs.

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